CD1a-Targeted PD-1 Agonists for Localised Immunosuppression in Atopic Dermatitis

  • IMC-U120AI is a novel, first in class skin targeted PD-1 agonist bispecific (ImmTAI) to provide localised immune inhibition for the treatment of Atopic Dermatitis
  • CD1a-targeted PD-1 agonists show potent inhibition of CD4+T-cells and NK cells
  • IMC-U120AI is the first Immunocore ‘universal’ therapy