Simon Jiang
VP of Biology, Head of Scientific Engagement LIDE Biotech
Seminars
Wednesday 10th December 2025
A Translational Approach to Evaluate T Cell Engagers and Bispecific Antibodies in Humanised Animal Models
2:00 pm
- Development of Co-inoculated tumour/PBMC animal models to assess the efficacy and immune-mediated mechanisms of T Cell
- Engagers and Bispecific Antibodies.
- Application of a humanised miniPDX platform to evaluate TCE in fresh patient-derived samples from multiple myeloma and SLE.
- Establishment of clinically relevant animal models to support candidate selection and optimisation for next generation TCE therapies.
