Marc Lenoir
Associate Director, Biologics Engineering AstraZeneca
Associate Director within Biologics Engineering (BE) at AstraZeneca based in Cambridge UK working on engineering innovative antibody-based modalities for the treatment of cancer. Has more than 10 years’ experience in the field of antibody and TCR engineering.
Seminars
Thursday 10th December 2026
Unlocking Safe & Potent T-Cell Engagers by Applying Rational Design Principles to Maximise Efficacy & Minimise Toxicity
1:30 pm
- Tuning affinity, valency and format to efficiently form immune synapse
- Engineering CD8 T-cell selectivity to minimise CRS and ICANS without compromising therapeutic potency
- Presenting pre-clinical data on leading programs entering clinical trial