Activating NK Cell Receptors as Trigger Molecules for Bispecific Antibodies to Enhance Anti-Tumour NK Cell Responses

  • Evaluating preclinical case studies of NKG2D or NKp30 engaging bispecific antibodies
  • Synergy with FcγRIIIA engagement – discussing multispecific molecules and impact of molecule architecture vs combination approaches to improve synapse quality and PK profile
  • Exploring opportunities for combination with adoptive NK cell transfer using a novel NK cell expansion technology for enhanced therapeutic impact